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2. Morning NPH and bolus, evening bolus, bedtime NPH (2)

Category: Management Topic: Health
2. Morning NPH and bolus, evening bolus, bedtime NPH (2)

Image: free stock via Unsplash · topic Health

Approximate Sensitivity Factor (mmol/l): 1.1, 1.4

Average Total Daily Insulin (Basal + Bolus units): 100

Approximate Sensitivity Factor (mg/dl): 15, 20

Approximate Sensitivity Factor (mmol/l): 0.8, 1.1

Average Total Daily Insulin (Basal + Bolus units): 120

Approximate Sensitivity Factor (mg/dl): 13, 17

Approximate Sensitivity Factor (mmol/l): 0.7, 1.0

Average Total Daily Insulin (Basal + Bolus units): 140

Approximate Sensitivity Factor (mg/dl): 11, 15

Approximate Sensitivity Factor (mmol/l): 0.6, 0.8

Average Total Daily Insulin (Basal + Bolus units): 160

Approximate Sensitivity Factor (mg/dl): 10, 12

Approximate Sensitivity Factor (mmol/l): 0.5, 0.7

Average Total Daily Insulin (Basal + Bolus units): 180

Approximate Sensitivity Factor (mg/dl): 9, 11

Approximate Sensitivity Factor (mmol/l): 0.5, 0.6

Average Total Daily Insulin (Basal + Bolus units): 200

Approximate Sensitivity Factor (mg/dl): 8, 10

Approximate Sensitivity Factor (mmol/l): 0.4, 0.6

Medtronic In the Past 20 Minutes

Rising <3 mg/dL/min [0.17 mmol/L]

Rising 2-3 mg/dL/min [0.11-0.17 mmol/L]

Rising 1-2 mg/dL/min [0.06-0.11 mmol/L]

n/a

n/a

n/a

Falling 1-2 mg/dL/min

Falling 2-3 mg/dL/min [0.11-0.17 mmol/L]

Falling 2-3 mg/dL/min [0.11-0.17 mmol/L]

Falling <3 mg/dL/min [0.17 mmol/L]

Dexcom In the Past 15 Minutes

n/a

Rising <3 mg/dL/min [0.17 mmol/L]

Rising 2-3 mg/dL/min [0.11-0.17 mmol/L]

Rising 1-2 mg/dL/min [0.06-0.11 mmol/L]

Changing <1 mg/dL/min [0.06 mmol/L]

Falling 1-2 mg/dL/min [0.06-0.11 mmol/L]

Falling <2 mg/dl/min [0.11-0.16 mmol/l]

Rising <3 mg/dL/min [0.17 mmol/L]

n/a

Libre

n/a

n/a

Rising <2 mg/dl/min [0.11-0.16 mmol/l]

Rising 1-2 mg/dL/min [0.06-0.11 mmol/L]

Changing <1 mg/dL/min [0.06 mmol/L]

Falling 1-2 mg/dL/min [0.06-0.11 mmol/L]

Falling <2 mg/dl/min [0.11-0.16 mmol/l]

n/a

n/a

Eversense In the Past 20 Minutes

n/a

n/a

Rising <2 mg/dl/min [0.11-0.16 mmol/l]

Rising 1-2 mg/dL/min [0.06-0.11 mmol/L]

Changing <1 mg/dL/min [0.06 mmol/L]

Falling 1-2 mg/dL/min [0.06-0.11 mmol/L]

n/a

n/a

Current Trend

Rising Very Fast

Rising Fast

Rising Modestly

Falling Modestly

Falling Fast

Falling Very Fast

CGM Arrow Designation

Medtronic: Dexcom: Libre: (n/a) Eversense: (n/a)

Medtronic: Dexcom: Libre: Eversense

Medtronic: Dexcom: Libre: Eversense

Medtronic: Dexcom: Libre: Eversense

Medtronic: Dexcom: Libre: Eversense

Medtronic: Dexcom: Libre: (n/a) Eversense: (n/a)

Adjust Usual Dose to Offset

Add enough to usual bolus to offset 75 mg/dL [4.2 mmol/L] rise

Add enough to usual bolus to offset 50 mg/dL [2.8 mmol/L] rise

Add enough to usual bolus to offset 25 mg/dL [1.4 mmol/L] rise

Subtract enough from usual bolus to offset 25 mg/dL [1.4 mmol/L] fall

Subtract enough from usual bolus to offset 50 mg/dL [2.8 mmol/L] fall

Subtract enough from usual bolus to offset 75 mg/dL [4.2 mmol/L] fall

Table 7-8. How Different Systems Handle IOB

Device : Accu-Chek/Roche

What It Does with IOB : Calculates the correction bolus required to reach predicted or desirable glucose level given the amount of time since the last bolus was given.

Device : Insulet/OmniPod

What It Does with IOB : Deducts IOB from total meal + correction dose.

Device : Medtronic

What It Does with IOB : Deducts IOB from correction bolus only. Meal portion of the bolus is never reduced by IOB.

Device : Tandem

What It Does with IOB : If the glucose entry is above the target blood sugar, the IOB is deducted from the correction bolus only; the meal portion of the bolus will not be reduced by IOB. If the glucose entry is below the target blood sugar, the meal dose will be reduced by IOB.

Device : Ypsomed

What It Does with IOB : Deducts IOB from total meal + correction bolus. IOB is calculated based on a linear insulin action profile rather than the usual curvilinear action.

Device : InPen

What It Does with IOB : If it has been ≤ 2hrs since last food bolus and BG >180 (10), IOB deducted from correction dose only. If >2hrs and BG is above target, IOB deducted from total food + correction dose. If BG is below target, IOB will be deducted from the food dose.

Table 7-9. IOB Based on Time Since Bolus Was Given

Time Since Bolus Was Given: 0.5 hr

Insulin Used Up: 10%

Insulin Still Working (IOB): 90%

Time Since Bolus Was Given: 1 hr

Insulin Used Up: 30%

Insulin Still Working (IOB): 70%

Time Since Bolus Was Given: 1.5 hrs

Insulin Used Up: 50%

Insulin Still Working (IOB): 50%

Time Since Bolus Was Given: 2 hrs

Insulin Used Up: 65%

Insulin Still Working (IOB): 35%

Time Since Bolus Was Given: 2.5 hrs

Insulin Used Up: 80%

Insulin Still Working (IOB): 20%

Time Since Bolus Was Given: 3 hrs

Insulin Used Up: 90%

Insulin Still Working (IOB): 10%

Time Since Bolus Was Given: 3.5 hrs

Insulin Used Up: 95%

Insulin Still Working (IOB): 5%

Time Since Bolus Was Given: 4 hrs

Insulin Used Up: 100%

Insulin Still Working (IOB): 0%

Table 7-10. Simplified IOB Calculation Based on a Three-Hour Duration of Insulin Action

Time Since Bolus Was Given: 1 hr

Insulin Used Up: 33%

Insulin Still Working (IOB): 67%

Time Since Bolus Was Given: 2 hrs

Insulin Used Up: 67%

Insulin Still Working (IOB): 33%

Time Since Bolus Was Given: 3 hrs

Insulin Used Up: 100%

Insulin Still Working (IOB): 0%

Table 7-11. Simplified IOB Calculation Based on a Four-Hour Duration of Insulin Action

Time Since Bolus Was Given: 1 hr

Insulin Used Up: 25%

Insulin Still Working (IOB): 75%

Time Since Bolus Was Given: 2 hrs

Insulin Used Up: 50%

Insulin Still Working (IOB): 50%

Time Since Bolus Was Given: 3 hrs

Insulin Used Up: 75%

Insulin Still Working (IOB): 25%

Time Since Bolus Was Given: 4 hrs

Insulin Used Up: 100%

Insulin Still Working (IOB): 0%

Table 7-12. Simplified IOB Calculation Based on a Five-Hour Duration of Insulin Action

Time Since Bolus Was Given: 1 hr

Insulin Used Up: 20%

Insulin Still Working (IOB): 80%

Time Since Bolus Was Given: 2 hrs

Insulin Used Up: 40%

Insulin Still Working (IOB): 60%

Time Since Bolus Was Given: 3 hrs

Insulin Used Up: 60%

Insulin Still Working (IOB): 40%

Time Since Bolus Was Given: 4 hrs

Insulin Used Up: 80%

Insulin Still Working (IOB): 20%

Time Since Bolus Was Given: 5 hrs

Insulin Used Up: 100%

Insulin Still Working (IOB): 0%

Time: 8:00 a.m.

Blood Sugar: 238 mg/dl (13.2 mmol/l) Correction bolus given

Time: 8:30

Blood Sugar: 235 (13.1)

Time: 9:00

Blood Sugar: 222 (12.3)

Time: 9:30

Blood Sugar: 174 (9.8)

Time: 10:00

Blood Sugar: 141 (7.8)

Time: 10:30

Blood Sugar: 125 (6.9)

Time: 11:00

Blood Sugar: 118 (6.6)

Time: 11:30

Blood Sugar: 111 (6.2)

Time: 12:00 p.m.

Blood Sugar: 112 (6.2)

Table 7-13. Bolus Multipliers for Physical Activity

Activity Multipliers

: Low Intensity (RPE 8, 11)

Short Duration (15, 30 Minutes): 0.90 (10% reduction)

Moderate Duration (40, 60 Minutes) 0.80 (20% reduction)

Long Duration (<60 Minutes): 0.70 (30% reduction)

Activity Multipliers

: Moderate Intensity (RPE 12, 15)

Short Duration (15, 30 Minutes): 0.75 (25% reduction)

Moderate Duration (40, 60 Minutes) 0.67 (33% reduction)

Long Duration (<60 Minutes): 0.50 (50% reduction)

Activity Multipliers

: High Intensity (RPE 16, 18)

Short Duration (15, 30 Minutes): 0.67 (33% reduction)

Moderate Duration (40, 60 Minutes) 0.50 (50% reduction)

Long Duration (<60 Minutes): 0.33 (67% reduction)

Table 7-14. Rating of Perceived Exertion

Very, very light 8

Very light

Fairly light

Somewhat hard

Hard

Very hard

Very, very hard

Note: Very, very light activities constitute little more than resting and typically do not require any insulin adjustments. Very, very hard activities (maximal intensity) are usually “anaerobic,” meaning they cannot be performed for more than a few minutes and often cause a short-term rise in blood sugar levels.

Table 7-15. Optimal Bolus Timing Based on Glycemic Index of Food

High-GI food

Bolus well before eating

Moderate-GI food

Bolus soon before eating

Low-GI food, prolonged or very large meals

Bolus after eating, or spread out delivery

Table 7-16. Bolus Timing Based on GI and Premeal Blood Sugar

Bolus Timing in Relation to Meal: BG above target

High GI: 35-45 minutes prior

Moderate GI: 20-25 minutes prior

Low GI, Prolonged or Large Meal: 0-10 minutes prior

Bolus Timing in Relation to Meal: BG on target

High GI: 20-30 minutes prior

Moderate GI: 5-10 minutes prior

Low GI, Prolonged or Large Meal: 5-15 minutes after

Bolus Timing in Relation to Meal: BG below target

High GI: 0-15 minutes prior

Moderate GI: 5-10 minutes after

Low GI, Prolonged or Large Meal: 20-30 minutes after

Table 8-1. Protein Content of Protein-Rich Foods

Protein Source: sirloin steak

Serving Size: 4 oz

Protein Content (grams): 34 g protein

Protein Source: chicken breast

Serving Size: 3 oz

Protein Content (grams): 26 g protein

Protein Source: cooked ground turkey

Serving Size: 3 oz

Protein Content (grams): 22 g protein

Protein Source: cooked ground beef

Serving Size: 3 oz

Protein Content (grams): 22 g protein

Protein Source: tuna (drained)

Serving Size: 3 oz

Protein Content (grams): 22 g protein

Protein Source: salmon

Serving Size: 3 oz

Protein Content (grams): 19 g protein

Protein Source: cottage cheese

Serving Size: 4 oz

Protein Content (grams): 14 g protein

Protein Source: tofu

Serving Size: 3 oz

Protein Content (grams): 13 g protein

Protein Source: skim or 1% milk

Serving Size: 8 oz

Protein Content (grams): 9 g protein

Protein Source: lima / kidney beans

Serving Size: half cup

Protein Content (grams): 7 g protein

Protein Source: cheese

Serving Size: 1 oz

Protein Content (grams): 7 g protein

Protein Source: 1 whole egg

Serving Size: large

Protein Content (grams): 6 g protein

Protein Source: low fat yogurt

Serving Size: 4 oz

Protein Content (grams): 5 g protein

Protein Source: Greek yogurt

Serving Size: 8 oz

Protein Content (grams): 20 g protein

Protein Source: nut butter

Serving Size: 2 Tbsp

Protein Content (grams): 8 g protein

Table 8-2. Carbs to Maintain Blood Sugar During Typical Cardiovascular Exercise

Carbohydrate Needed (grams) per Sixty Minutes of Physical Activity

Low Intensity

50 lbs (23 kg): 5-8 g

100 lbs (45 kg): 10-16 g

150 lbs (68 kg): 15-25 g

200 lbs (91 kg): 20-32 g

250 lbs (114kg): 25-40 g

300 lbs. (135 kg): 30-48 g

Moderate Intensity

50 lbs (23 kg): 10-13 g

100 lbs (45 kg): 20-26 g

150 lbs (68 kg): 30-39 g

200 lbs (91 kg): 40-52 g

250 lbs (114kg): 50-65 g

300 lbs. (135 kg): 60-78 g

High Intensity

50 lbs (23 kg): 15-18 g

100 lbs (45 kg): 30-36 g

150 lbs (68 kg): 45-55 g

200 lbs (91 kg): 60-72 g

250 lbs (114kg): 75-90 g

300 lbs. (135 kg): 90-118 g

Table 9-1

Weight in lbs (kg): <60 (<28)

Amount Each Gram of Carb Should Raise Your BG in mg/dl (mmol/l): 6-10 (0.33-0.55)

Weight in lbs (kg): 60-100 (29-47)

Amount Each Gram of Carb Should Raise Your BG in mg/dl (mmol/l): 5 (0.28)

Weight in lbs (kg): 101-160 (48-76)

Amount Each Gram of Carb Should Raise Your BG in mg/dl (mmol/l): 4 (0.22)

Weight in lbs (kg): 161-220 (77-105)

Amount Each Gram of Carb Should Raise Your BG in mg/dl (mmol/l): 3 (0.17)

Weight in lbs (kg): <220 (<105)

Amount Each Gram of Carb Should Raise Your BG in mg/dl (mmol/l): 2 (0.11)

Table 9-2. Proper Treatment for Low Blood Sugar (Based on Body Weight and Blood Sugar Level), with a Target BG of 120 (6.7)

Blood Sugar mg/dl

(mmol/l)

Weight : <60 lbs (<28 kg)

80s (4.4, 5): 4 g

70s (3.9, 4.3): 5 g

60s (3.3, 3.8): 7 g

50s (2.8, 3.2): 8 g

40s (2.2, 2.7) : 10 g

<40 (<2.2): 12 g

Blood Sugar mg/dl

(mmol/l)

Weight : 60-100 (28-47)

80s (4.4, 5): 7 g

70s (3.9, 4.3): 9 g

60s (3.3, 3.8): 11 g

50s (2.8, 3.2): 13 g

40s (2.2, 2.7) : 15 g